Purple Foxglove was historically used to treat which conditions?

Prepare for the Prehospital Emergency Pharmacology Test. Utilize flashcards and a variety of questions, each with explanations. Ensure success in your exam!

Multiple Choice

Purple Foxglove was historically used to treat which conditions?

Explanation:
Purple Foxglove contains cardiac glycosides that were historically used to treat heart failure and related edema (dropsy). The way they work is by inhibiting the Na+/K+-ATPase pump in heart muscle cells, which raises intracellular calcium and strengthens each heartbeat (positive inotropy). They also increase vagal tone, which can slow the heart and help control certain rapid rhythms. Because these effects address the weakened pumping and edema seen in heart disease, they were used for dropsy and other heart-related issues. They aren’t used for allergies, digestive ulcers, or skin infections, which involve different systems and treatments.

Purple Foxglove contains cardiac glycosides that were historically used to treat heart failure and related edema (dropsy). The way they work is by inhibiting the Na+/K+-ATPase pump in heart muscle cells, which raises intracellular calcium and strengthens each heartbeat (positive inotropy). They also increase vagal tone, which can slow the heart and help control certain rapid rhythms. Because these effects address the weakened pumping and edema seen in heart disease, they were used for dropsy and other heart-related issues. They aren’t used for allergies, digestive ulcers, or skin infections, which involve different systems and treatments.

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